Microwave and flow syntheses of Pseudomonas quinolone signal (PQS) and analogues.
نویسندگان
چکیده
Expedient syntheses of Pseudomonas quinolone signal (PQS) and related structural analogues using microwave and flow methods are reported.
منابع مشابه
Structure-activity analysis of the Pseudomonas quinolone signal molecule.
We synthesized a range of PQS (Pseudomonas quinolone signal; 2-heptyl-3-hydroxy-4(1H)-quinolone) analogues and tested them for their ability to stimulate MvfR-dependent pqsA transcription, MvfR-independent pyoverdine production, and membrane vesicle production. The structure-activity profile of the PQS analogues was different for each of these phenotypes. Certain inactive PQS analogues were als...
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 1 شماره
صفحات -
تاریخ انتشار 2011